Hospira offers a wide range of ready-to-use and low-risk products in support of efforts to comply with the tighter controls on the compounding of sterile products required by USP Chapter <797>. These products include:
ADD-Vantage® System
FirstChoice® Premixes
Nutrimix® Dual Chamber Flexible Container
Prefilled Syringes
Carpuject® Syringe System
Ansyr® Emergency Syringes
LifeShield® Abboject® Emergency Syringes
Prefilled Flush Syringes
Product Risk Comparison Chart
According to the American Journal of Health-System Pharmacy:
“Another effective means of reducing the level of risk for CSPs [compounded sterile preparations] is the use of...unit-of-use closed transfer packaging (eg, Minibag Plus and ADD-Vantage).”1
The ADD-Vantage admixture system helps support USP <797> compliance efforts.
ADD-Vantage® System
- Sterile components
- Closed system
- Activated just prior to administration
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According to ASHP Guidelines: Minimum Standard for Pharmacies in Hospitals:
“Whenever possible, medications shall be available for inpatient use in single-unit packages and in a ready-to-administer form. Manipulation of medications before administration…should be minimized.”2
FirstChoice Premixes help answer the challenge to do more to avoid the potential for contamination during traditional admixing and therefore bolster any USP <797> compliance strategy. Hospira’s ready-to-use premixes are an excellent first choice for avoiding traditional admixing and the associated risks.
FirstChoice Premixes
- No admixing
- Convenient, ready-to-use
- Avoids potential contamination that can occur during traditional admixing
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According to USP Chapter <797>: ”Examples of low risk compounding [include]…manually measuring and mixing no more than three manufactured products to…nutritional solutions.”3
Because it allows for mixing within a single closed container, the Nutrimix Dual Chamber Flexible Container helps reduce the risk of potential contamination during admixing. For pharmacists preparing nutritional products, the Nutrimix Dual Chamber Flexible Container can be an important part of a USP <797> compliance strategy.
Nutrimix® Dual Chamber Flexible Container
- Closed-system design
- Enables mixing within a single closed container
- Guards against accidental touch contamination
- Helps reduce the risk of contamination and increase confidence in compliance
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According to the ASHP Guidelines on Preventing Medication Errors in Hospitals:
“Pharmacists should dispense medications in ready-to-administer dosage forms whenever possible. The unit-dose system is strongly recommended as the preferred method of drug distribution.”4
A USP <797> compliance strategy that includes medications in ready-to-administer dosage forms makes good sense. Prefilled syringes from Hospira can be an important part of that strategy.
Carpuject® Syringe System
- Ready-to-use prefilled cartridges
- Reduces risk because no preparation is necessary
Ansyr® and LifeShield® Abboject® Emergency Syringes
- Prefilled
- Ready-to-use, when seconds count
Prefilled Flush Syringes
- Ready-to-use
- Maintain IV lines while reducing potential contamination risk
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Hospira’s ready-to-use and low-risk products help support a
USP Chapter <797> compliance strategy.
References
1. Kastango ES, Bradshaw BD. USP chapter 797: establishing a practice standard for compounding sterile preparations in pharmacy. Am J Health Syst Pharm. 2004;61:1928-1938.
2. American Society of Health-System Pharmacists. ASHP guidelines: minimum standard for pharmacies in hospitals. In: Best Practices for Hospital & Health-System Pharmacy. Position & Guidance Documents of ASHP. 2004-2005 ed. Bethesda, Md: American Society of Health-System Pharmacists; 2004:325-330.
3. USP General Chapter <797>. The current United States Pharmacopeia, 27th rev, and the National Formulary, 22nd ed, and Supplements. Rockville, Md: The United States Pharmacopeial Convention, 2004.
4. American Society of Health-System Pharmacists. ASHP guidelines on preventing medication errors in hospitals. In: Best Practices for Hospital & Health-System Pharmacy. Position & Guidance Documents of ASHP. 2004-2005 ed. Bethesda, Md: American Society of Health-System Pharmacists; 2004:155-163.